Tom Chang

Publications | Abstracts

• Anderson, S.N, Nziko, Vincent de Paul Nzuwah, , Chang, C.T, Hengge, A.C, (2014). Enhancing safety in academic research laboratories: Creating a student based safety committee. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY *

An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

Publications | Book Chapters

• Wang, J., Chang, C.T, (2007). Design, Chemical Synthesis, and Antibacterial Activity of Kanamycin and Neomycin Class Aminoglycoside Antibiotics: Aminoglycoside Antibiotics . John Wiley & Sons, Inc.
• Wang, J., Chang, C.T, (2007). Glycodiversification for the Synthesis of Kanamycin and Neomycin Class Aminoglycoside Antibiotics: Frontiers in Carbohydrate Chemistry. ACS Symposium Series
• Wang, J., Chang, C.T, (2005). Systematic Synthesis of Aminosugars and Their Stereoselective Glycosylation: Carbohydrate Drug Design. ACS Symposium Series

An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

Publications | Journal Articles

Academic Journal

• Chang, C.T, Poudyal, N., Verdugo, D.A, Peña, F., Stehberg, J., Retamal, M.A, (2023). KI04 an Aminoglycosides-Derived Molecule Acts as an Inhibitor of Human Connexin46 Hemichannels Expressed in HeLa Cells. Biomolecules
• Takemoto, J.Y, Liao, T., Chen, C., Chang, C.T, Lin, Y., Mesobiliverdin IXα-Enriched Microalgae Feed Improves Gut Health in Weaning Piglets Under LPS Challenge. Journal of Animal Physiology and Animal Nutrition
• Wang, W., Chang, C.T, Zhang, Q., (2022). 1, 4‐Naphthoquinone Analogs and Their Application as Antibacterial Agents. ChemistrySelect., 7, e202203330.
• Takemoto, J.Y, Altenberg, G.A, Poudyal, N., Subedi, Y., Chang, C.T, (2022). Amphiphilic aminoglycosides: Modifications that revive old natural product antibiotics. Front. Microbiol. , September 23.
• Lin, Y., Takemoto, J.Y, Chang, C.T, Peng, C., (2022). Mesobiliverdin IXα ameliorates osteoporosis via promoting osteogenic differentiation of mesenchymal stem cells. Biochemical and Biophysical Research Communications, 619, 56-61.
• Subedi, Y.P, Altenberg, G.A, Chang, C.T, (2021). Advances in the development of connexin hemichannel inhibitors selective toward Cx43. Future Medicinal Chemistry, 587a.
• Natha, C.M, Vemulapalli, V., Fiori, M., Chang, C.T, Altenberg, G.A, (2021). Connexin Hemichannel Inhibitors with a Focus on Aminoglycosides. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 166115.
• Subedi, Y.P, Kjellgren, A., Roberts, P., Montgomery, H., Thackeray, N., Fiori, M.C, Altenberg, G.A, Chang, C.T, (2020). Amphiphilic aminoglycosides with increased selectivity for inhibition of connexin 43 (Cx43) hemichannels.. Eur. J. Med. Chem., 112602.
• Zhang, W., Rhodes, J., Garg, A., Takemoto, J.Y, Qi, X., Harihar, S., Chang, C.T, Moon, K., Zhou, A., (2020). Label-free Discrimination and Quantitative Analysis of Oxidative Stress Induced Cytotoxicity and Potential Protection of Antioxidants Using Raman Spectroscopy and Machine Learning. Analytica Chimica Acta, 1128, 221-230.
• Kjellgren, A., Fiori, M.C, AlFindee, M.N, Subedi, Y.P, Krishnan, S., Chang, C.T, Altenberg, G.A, (2020). Selective Inhibition of Different Isoforms of Connexin Hemichannels by New Aminoglycosides. Biophysical Journal, 118, supplemental 1 587a.
• Pandey, U., Subedi, Y.P, Alfindee, M.N, Shepherd, T., Chang, C.T, (2020). An Alternative and Facile Synthetic Approach for the Precursors of 3- and 6-Aminosugar Donors and Study of One-Pot Glycosyltrasferation . Chem Lett, 49, 99-102.
• Subedi, Y.P, Pandey, U., Alfindee, M.N, Montgomery, H., Roberts, P., Wight, J., Nichols, G., Grilley, M.M, Takemoto, J.Y, Chang, C.T, (2019). Scalable and cost-effective tosylation-mediated synthesis of antifungal and fungal diagnostic 6''-Modified amphiphilic kanamycins. Eur J Med Chem, 182, 111639.
• Alfindee, M.N, Subedi, Y.P, Grilley, M.M, Takemoto, J.Y, Chang, C.T, (2019). Antifungal Activities of 4″,6″-Disubstituted Amphiphilic Kanamycins. Molecules, 24:10, e1882. doi: 10.3390/molecules24101882
• Chang, C.T, Takemoto, J.Y, Zhan, J., (2019). Natural Bioactive Compounds. Israel Journal of Chemistry, 59, 325-326. doi: https://doi.org/10.1002/ijch.201900050
• Subedi, Y.P, Paul, R., Grilley, M.M, Takemoto, J.Y, Chang, C.T, (2019). Development of fungal selective amphiphilic kanamycin: cost effective synthesis and use of fluorescent analogs for mode of action investigation. ACS Infect Diseases, 5, 473-483. doi: https://doi.org/10.1021/acsinfecdis.8b00327
• Kjellgren, A., Fiori, M.C, AlFindee, M.N, Subedi, Y.P, Krishnan, S., Chang, C.T, Altenberg, G.A, (2019). Inhibition of Connexin Hemichannels by New Aminoglycosides without Antibiotic Activity. Biophysical Journal, 116, supplemental 1 250a.
• Takemoto, J.Y, Chang, C.T, Chen, D., Hinton, G., (2019). Heme-derived bilins. Israel Journal of Chemistry, 59, 378-386. doi: DOI: 10.1002/ijch.201800167
• Subedi, Y.P, Chang, C.T, (2019). Cationic Anthraquinone Analogs as Selective Antimicrobials. Microbiology Insights
• Subedi, Y.P, AlFindee, M.N, Takemoto, J.Y, Chang, C.T, (2018). Antifungal amphiphilic kanamycins: new life for an old drug. MedChemComm, 9:6, 909-919.
• AlFindee, M.N, Subedi, Y.P, Fiori, M.C, Krishnan, S., Kjellgren, A., Altenberg, G.A, Chang, C.T, (2018). Inhibition of Connexin Hemichannels by New Amphiphilic Amino-glycosides without Antibiotic Activity. ACS Med. Chem. Lett, 9, 697-701.
• AlFindee, M.N, Zhang, Q., Subedi, Y.P, Shrestha, J., Kawasaki, Y., Grilley, M.M, Takemoto, J.Y, Chang, C.T, (2018). One-step Synthesis of Carbohydrate Esters as Antibacterial and Antifungal Agents. Bioorg. Med. Chem., 26, 765.
• Subedi, Y.P, AlFindee, M.N, Shrestha, J., Becker, G., Grilley, M.M, Takemoto, J.Y, Chang, C.T, (2018). Synthesis and biological activity investigation of azole and quinone hybridized phosphonates. Bioorg. Med. Chem. Lett., 28, 3034.
• Subedi, Y.P, AlFindee, M.N, Shrestha, J., Chang, C.T, (2018). Tuning the Biological Activity of Cationic Anthraquinone Analogues Specifically toward Staphylococcus aureus. Eur. J. Med. Chem., 127, 683.
• Takemoto, J.Y, Wegulo, S., Yuen, G.Y, Stevens, J.A, Jochum, C.C, Chang, C.T, Kawasaki, Y., Miller, G.A, (2018). Suppression of wheat fusarium head blight by novel amphiphilic aminoglycoside fungicide K20 . Fungal Biology, 122, 465-470. doi: doi.org/10.1016/j.funbio.2017.12.001
• Prokhorova, I., Altman, R.B, Djumagulov, M., Shrestha, J.P, Urzhumtsev, A., Ferguson, A., Chang, C.T, Yusupov, M., Blanchard, S., Yusupov, G., (2017). Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. USA
• Shrestha, J., Colman, B., Kawasaki, Y., Nziko, V., Subedi, Y., Takemoto, J.Y, Chang, C.T, (2017). Synthesis and bioactivity investigation of quinone-based dimeric cationic triazolium amphiphiles selective against resistant fungal and bacterial pathogens. Eur. J. Med. Chem., 126, 596.
• Sun, L., Wang, S., Zhang, S., Shao, L., Zhang, Q., Skidmore, C., Chang, C.T, Yu, D., Zhan, J., (2016). Characterization of three tailoring enzymes in dutomycin biosynthesis and generation of a potent antibacterial analogue. ACS Chemical Biology , 11, 1997.
• Zhang, Q., Alfindee, M., Shrestha, J., Nziko, V., Kawasaki, Y., Peng, X., Takemoto, J., Chang, C.T, (2016). Divergent Synthesis of Three Classes of Antifungal Amphiphilic Kanamycin Derivatives. JOC, 81, 10651.
• Peng, X., Takemoto, J.Y, Chang, C.T, (2016). Divergent synthesis of three classes of antifungal amphiphilic kanamycin derivatives. Journal of Organic Chemistry, 81:22, 10651-10663.
• Zhang, Q., Chang, C.T, (2015). Divergent and Facile Lewis Acid-Mediated Synthesis of N-Alkyl 2-aminomethylene-1,3-indanediones and 2-Alkylamino-1,4-Naphthoquinones. Tetrahedron Lett, 56, 893.
• Shrestha, J., Subedi, Y., Chen, L., Chang, C.T, (2015). Mode of Action Study of Cationic Anthraquinone Analog: A New Class of Highly Potent Anti-cancer Agent. MedChemComm, 2012.
• Fosso, M., AlFindee, M., Zhang, Q., Nziko, V., Kawasaki, Y., Shrestha, S., Bearss, J., Gregory, R., Takemoto, J., Chang, C.T, (2015). Structure–Activity Relationships for Antibacterial to Antifungal Conversion of Kanamycin to Amphiphilic Analogues. J Org Chem, 80, 4398.
• Shrestha, S.K, Grilley, M.M, Anderson, T., Dhiman, C., Oblad, J., Chang, C.T, Sorensen, K.N, Takemoto, J.Y, (2015). In vitro antifungal synergy between amphiphilic aminoglycoside K20 and azoles against Candida species and Cryptococcus neoformans. Med Mycol
• Zhang, Q., Peng, X., Grilley, M.M, Takemoto, J.Y, Chang, C.T, (2015). Using fluorogenic probes for the investigation of selective biomass degradation by fungi. Green Chem, 17, 1918-1925.
• Shrestha, S.K, Chang, C.T, Meissner, N., Oblad, J., Shrestha, J.P, Sorensen, K.N, Grilley, M.M, Takemoto, J.Y, (2014). Antifungal amphiphilic aminoglycoside K20: bioactivities and mechanism of action. Frontiers in Microbiology, 5:271, 1-12. doi: doi: 10.3389/fmicb.2014.00671
• Chang, C.T, Takemoto, J.Y, (2014). Antifungal amphiphilic aminoglycosides. Med. Chem. Comm., 5, 1048-1057.
• Nziko, , Fosso, M., Chang, C.T, (2014). Quantitative structure activity relationship analysis of antibacterial cationic anthraquinone analogs using Hansch and Fujita models. Med. Chem. Res, 23, 5058-5062.
• Shretha, J., Fosso, M.Y, Bearss, J., Chang, C.T, (2014). Synthesis and anticancer structure activity relationship investigation of cationic anthraquinone analogs. Eur. J. Med. Chem. , 77, 96-102.
• Zhang, Q., Shretha, J., Chang, C.T, (2014). Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent. Tetrahedron Lett, 55, 1839-1842.
• Udumula, U., Ham, Y., Fosso, M., Chen, K., Rai, R., Zhang , J., Li, J., Chang, C.T, (2013). Investigation of Antibacterial Mode of Action for Traditional and Amphiphilic Aminoglycosides.. Bioorg Med Chem Lett, 23, 1671-1675.
• Ito, T., Chen, D., Chang, C.T, Kenmochi, T., Saito, T., Suzuki, S., Takemoto, J.Y, (2013). Meso-biliverdin IX and Biliverdin IX Provide Cytoprotection of Rat Pancreatic Islets. Frontiers in Pharmacology 4, 1-8.
• Shretha, J., Chang, C.T, (2013). Safe and Easy Route for the Synthesis of 1,3-Dimethyl-1,2,3-triazolium Salt and Investigation of Its Anticancer Activities. Bioorg Med Chem Lett, 23, 5909-5911.
• Lee, S.T, Green, B.T, Welch, K.D, Jordan, G.T, Zhang, Q., Panter, K.E, Hughe, D., Chang, C.T, Pfister, J.A, Gardner, D.R, (2013). Stereoselective Potencies and Relative Toxicities of γ-Coniceine, and N-Methylconiine Enantiomers. Chemical Research in Toxicology, 26, 616-621.
• Shrestha, S., Grilley, M.M, Fosso, M.Y, Chang, C.T, Takemoto, J.Y, (2013). Membrane lipid-modulated mechanism of action and non-cytotoxicity of novel fungicide aminoglycoside FG08. PloS one, 8:9, e73843.
• Mattis, V.B, Chang, C.T, Lorson, C.L, (2012). Analysis of a read-through promoting compound in a severe mouse model of Spinal Muscular Atrophy. Neurosci. Lett. , 525, 72-75.
• Fosso, M., Nziko, V., Chang, C.T, (2012). Chemical Synthesis of N-Aryl Glycosides. J. Carbohydr. Chem., 31, 603.
• Lee, S.T, Panter, K.E, Gardner, D.R, Green, B.T, Welch, K.D, Zhang, J., Chang, C.T, (2012). Development of a monoclonal antibody-based ELISA for the hedgehog inhibitors cyclopamine and cyclopamine-KAAD. J. Pharmaceut. Biomed. Anal., 66, 282-286.
• Fosso, M., Chen, K., Gregory, R., Chang, C.T, (2012). Library Synthesis and Antibacterial Investigation of Cationic Anthraquinone Analogs. ACS, 14, 231.
• Chan, K., Zhang, J., Chang, C.T, (2011). Mode of Action Investigation for the Antibacterial Cationic Anthraquinone Analogs.. Bioorg. Med. Chem. Lett. , 21, 6353.
• Zhang, J., Redman, N., Litke, P., Zeng, J., Zhan, J., Chan, K.Y, Chang, C.T, (2011). Synthesis and Antibacterial Activity Study of a Novel Class of Cationic Anthraquinone Analogs. Bioorganic Medicinial Chemistry, 19, 498-503.
• Tanifum, C.T, Zhang, J., Chang, C.T, (2010). Combination of Solid Phase and Solution Phase Synthesis of Oligosaccharides Using Sonication. Tetrahedron Letters, 51, 4323-4327.
• Zhang, J., Litke, A., Keller, K., Rai, R., Chang, C.T, (2010). Synthesis of Novel Aminoglycosides via Allylic Azide Rearrangement for Investigating the Significance of 2'-Amino Group. Bioorganic Medicinal Chemistry, 18, 1396-1405.
• Mattis, V.B, Ebert, A.D, Fosso, M.Y, Chang, C.T, Lorson, C.L, (2009). Delivery of a read-through inducing compound, TC007, lessens the severity of a SMA animal model. Human Molecular Genetics, 18, 3906-3913.
• Zhang, J., Chang, C.T, (2009). Divergent Synthesis of Three Classes of Aryl N-Glycosides by Solvent Control. Journal of Organic Chemistry, 74, 685-695.
• Zhang, J., Chang, C.T, (2009). One-pot Synthesis of 1- and 2-Substituted Naphtho[2,3-d][1,2,3]triazole-4,9-diones. Journal of Organic Chemistry, 74, 4414-4417.
• Chang, C.T, (2009). Predictable Enzymatic Glycosylation. Chemical Biology, 16, 579-580.
• Tanifum, C.T, Chang, C.T, (2009). Sonication-Assisted Oligomannosides Syntheses. Journal of Organic Chemistry, 74, 4414-4417.
• Zhang, J., Keller, K., Takemoto, J.Y, Bensaci, M., Litke, A., Crzyryca, P.G, Chang, C.T, (2009). Synthesis and Combinational Antibacterial Study of 5"-Modified Neomycin. The Journal of Antibiotics, 62, 539-544.
• Lee, S.T, Gardner, D.R, Chang, C.T, Panter, K.E, Molyneux, R.J, (2008). Separation of Measurement of Plant Alkaloid Enantiomers by RF-HPLC Analysis of Their Fmoc-Alanine Analogs. Phytochemical Analysis, 19, 395-402.
• Zhang, J., Chiang, F., Wu, L., Czyryca, G.P, Li, D., Chang, C.T, (2008). Surprising Alteration of Antibacterial Activity of 5"-Modified Neomycin against Resistant Bacteria. Journal of Medicinal Chemistry, 51, 7563-7573.
• Zhang, J., Garrossian, M., Gardner, D., Garrossian, A., Chang, Y., Kim, Y.K, Chang, C.T, (2008). Synthesis and Anticancer Activity Studies of Cyclopamine Derivatives. Bioorganic & Medicinal Chemistry Letters, 18, 1359-1363.
• Li, J., Chiang, F., Chen, H., Chang, C.T, (2007). Investigation of the Regioselectivity for Staudinger Reaction and Its Application for the Synthesis of Aminoglycosides with N-1 Modification. J. Org. Chem., 72, 4055-4066.
• Zhang, J., Chen, H., Chiang, F., Takemoto, J.Y, Bensaci, M., Chang, C.T, (2007). Sonication-Assisted Library Synthesis of Oxazolidinone-Carbohydrate Conjugates. J. Comb. Chem., 9, 17-19.
• Li, J., Wang, J., Chiang, F., Chen, H.N, Chang, C.T, (2007). Synthesis of Pyranmycin Derivatives with N-1 and O-6 Modifications. Bioorg. Med. Chem. , 15, 7711-7719.
• Deng, S., Chang, C.T, (2006). Acyl Migration for the Construction of Disaccharides. Synlett, 756-760.
• Rai, R., Chen, H., Czyryca, P.G, Li, J., Chang, C.T, (2006). Design and Synthesis of Pyrankacin: A Pyranmycin Class Broad Spectrum Aminoglycoside Antibiotic. Org. Lett., 8, 887-889.
• Mattis, V., Wang, J., Rai, R., Chang, C.T, Lorson, C.L, (2006). Novel Aminoglycosides Increase SMN Levels in Spinal Muscular Atrophy fibroblasts. Human Genetics , 120, 589-601.
• Li, J., Chang, C.T, (2006). Recent Development in the Synthesis of Novel Aminoglycoside Antibiotics. Anti-Infective Agents in Medicinal Chemistry , 5, 255-271.
• Lee, S.T, Wildeboer, K., Panter, K.E, Kem, W.R, Gardner, D.R, Molyneux, R.J, Chang, C.T, Soti, F., Pfister, J.A, (2006). Relative toxicities and neuromuscular nicotinic receptor agonistic potencies of anabasine enantiomers and anabaseine. Neurotoxicology and Teratology, 28, 220-228.
• Deng, S., Gandafharmath, U., Chang, C.T, (2006). Sonochemistry: A Powerful Way of Enhancing the Efficiency of Carbohydrate Synthesis. J. Org. Chem. , 71, 5179-5185.
• Lee, S.T, Molyneux, R.J, Panter, K.E, Chang, C.T, Gardner, D.R, Pfister, J.A, Garrossian, M., (2005). Ammodendrine and N-Methylammodendrine Enantiomers: Isolation, Optical Rotation, and Toxicity. J. Nat. Prod., 68, 681-685.
• Wang, J., Li, J., Chen, H., Chang, H., Tanifum, C.T, Liu, H., Czyryca, P.G, Chang, C.T, (2005). Glycodiversification for Optimization of the Kanamycin Class Aminoglycosides. J. Med. Chem. , 48, 6271-6285.
• Rai, R., Chang, H., Chen, H., Chang, C.T, (2005). Novel Method for the Synthesis of 3’,4’-Dideoxygenated Pyranmycin and Kanamycin Compounds, and Studies of Their Antibacterial Activity against Aminoglycoside Resistant Bacteria. J. Carbohydr. Chem. , 24, 131-143.
• Rai, R., McAlexander, I., Chang, C.T, (2005). Synthetic Glycodiversification: from Aminosugars to Aminoglycoside Antibiotics. Organic Preparations and Procedures International, 37, 337-375.
• Li, J., Chen, H., Chang, H., Wang, J., Chang, C.T, (2005). Tuning the Regioselectivity of Staudinger Reaction for the Facile Synthesis of Kanamycin and Neomycin Class Antibiotics with N-1 Modification. Org. Lett., 7, 3061-3064.
• Li, J., Wang, J., Czyryca, P.G, Chang, H., Orsak, T.W, Evanston, R., Chang, C.T, (2004). Application of Glycodiversification: Expedient Synthesis and Antibacterial Evaluation of a Library of Kanamycin B Analogs. Org. Lett., 6, 1381-1384.
• Elchert, B., Li, J., Wang, J., Hui, Y., Rai, R., Ptak, R., Ward, P., Takemoto, J.Y, Bensaci, M., Chang, C.T, (2004). Application of the Synthetic Aminosugars for Glycodiversification: Synthesis and Antimicrobial Studies of Pyranmycin. J. Org. Chem. , 69, 1513-1523.
• Wang, J., Li, J., Czyryca, P.G, Chang, H., Kao, J., Chang, C.T, (2004). Synthesis of an Unusual Branched-chain Sugar, 5-C-methyl-L-idopyranose for SAR Studies of Pyranmycins: Implications for the Future Design of Aminoglycoside Antibiotics. Bioorg. Med. Chem. Lett. , 14, 4389-4393.
• Wang, J., Elchert, B., Hui, Y., Takemoto, J.Y, Bensaci, M., Wennergren, J., Chang, H., Rai, R., Chang, C.T, (2004). Synthesis of Trehalose-based Compounds and Study of Their Antibacterial Activity against Mycobacterium smegmatis. Bioorg. Med. Chem. , 12, 6397-6413.
• Li, J., Wang, J., Hui, Y., Chang, C.T, (2003). Exploring the Optimal Site for Modification of Pyranmycin with the Extended Arm Approach. Org. Lett. , 5, 431-434.
• Leriche, C., He, X., Chang, C.T, Liu, H., (2003). Reversal of the Apparent Regiospecificity of NAD(P)H-Dependent Hydride Transfer: The Properties of the Difluoromethylene Group, A Carbonyl Mimic. J. Am. Chem. Soc., 125, 6348-6349.
• Hui, y., Chang, C.T, (2002). A Convenient Divergent Synthesis of A library of Trehalosamine Analogs. Org. Lett. , 4, 2245-2248.
• Chen, H., Yamase, H., Zhao, L., Chang, C.T, Murakami, K., Liu, H., (2002). N, N-Dimetyltransferases, TylM1 and DesVI, Involved in the Biosynthesis of Mycaminose and Desosamine: Expression, Purification and Characterization. Biochemistry, 29, 9165-9183.
• Chang, C.T, Hui, Y., Elchert, B., Wang, J., Li, J., Rai, R., (2002). Pyranmycins, a novel class of aminoglycosides with improved acid stability: the SAR of D-pyranoses on ring III of pyranmycin. Org. Lett. , 4, 4603-4606.
• Hui, Y., Ptake, P., Paulman, R., Pallansch, M., Chang, C.T, (2002). Synthesis of Novel Guanidine Incorporated Aminoglycosides, Guanidinopyranmycins. Tetrahedron Lett. , 43, 9255-9257.
• Chang, C.T, Liu, H., (2002). Synthesis of TDP-3-amino-3,4,6-trideoxy-a-D-xylo-hexopyranose-The immediate precursor of TDP-a-D-desosamine. Bioorg. Med. Chem. Lett., 12, 1439-1496.
• Wang, J., Li, J., Tuttle, D., Takemoto, J., Chang, C.T, (2002). The synthesis of L-aminosugar and the studies of L-pyranoses on the ring III of pyranmycins. Org. Lett. , 4, 3997-4000.
• Chang, C.T, Clark, T., Ngaara, M., (2001). Novel and Convenient Method for the Synthesis of 2,6-Dideoxypyranoses, 3,6-Dideoxypyranoses, and Azido (amino) Analogs of 3,6-Dideoxypyranoses. Tetrahedron Lett. , 42, 6797-6801.
• Chang, C.T, Hui, Y., Elchert, B., (2001). Studies of the Stereoselective Reduction of Ketosugar (Hexosulose). Tetrahedron Lett, 42, 7019-7023.
• Chang, C.T, Zhao, L., Yamase, H., Liu, H., (2000). Des VI: A New Member of the Sugar N,N-Dimethyltransfrease Family Involved in the Biosynthesis of Desosamine. Angew. Chem. Int. Ed. , 39, 2160-2163.
• Chang, C.T, Chen, X., Liu, H., (1998). CDP-6-deoxy-6,6'-difluoro- a-D-glucose : A mechanism-Based Inhibitor for CDP-D-glucose 4,6-Dehydratase. J. Am. Chem. Soc., 120, 9698-9699.
• Gilbertson, S., Chang, C.T, (1997). A Modular Approach to Ligands for Asymmetric p-Allyl Palladium Catalyzed Additions. Chem Commun, 975.
• Gilbertson, S., Chang, C.T, (1995). Synthesis of New DisuA Modular Approach to Ligands for Asymmetric p-Allyl Palladium Catalyzed Additionsgar Phosphine Ligands and Their Use in Asymmetric Hydrogenation. J Org Chem, 63, 8424.
• Gilbertson, S., Chang, C.T, (1995). Synthesis of New Disugar Phosphine Ligands and Their Use in Asymmetric Hydrogenation. J Org Chem, 60, 6226.

Professional Journal

• Chang, C.T, Takemoto, J.Y, Chang, P., Alfindee, M.N, Lin, Y., (2021). Effects of mesobiliverdin IX alpha-enriched microalgae feed on gut health and microbiota of broilers. Front Vet Sci, 7, doi: 10.3389/fvets.2020.586813

Public or Trade Journal

• Takemoto, J.Y, Chang, C.T, Shrestha, S.K, Grilley, M.M, (2017). Aminoglycoside and azole compositions and methods, US Patent 9,669,044 B2, Issued June 6 2017. U.S. Patent and Trademark Office
• Takemoto, J.Y, Chen, D., Chang, C.T, (2015). Meso-biliverdin compositions and methods, US Patent 9242932 B2, Issued Jan 26 2016. United States Patent Office
• Takemoto, J.Y, Chen, D., Chang, C.T, Wood, J.L, (2015). Therapeutic meso-biliverdin IXalpha compositions and associated methods, US Patent 9119842 B2, Issued Sept 1 2015. US Patent and Trademark Office
• Takemoto, J.Y, Chen, D., Chang, C.T, Wood, J., (2014). Therapeutic compositions and associated methods, US20140079723 A1, WO2014043645A1 Issued March 20, 2014. US Patent and Trademark Office
• Chang, C.T, Takemoto, J.Y, (2009). New Aminoglycosides: synthesis and use as antifungals PCT/US2009/046827 . US Patent and Trademark Office

An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.

Publications | Other

Other

An asterisk (*) at the end of a publication indicates that it has not been peer-reviewed.